聚焦老年期抑郁障碍规范诊疗——《老年期抑郁障碍诊疗专家共识（2025版）》解读

Focus on standardized diagnosis and treatment of late life depression： interpretation of the "Expert consensus on diagnosis and treatment of late life depression （2025 edition）"

中文关键词:  老年期抑郁障碍  诊断  治疗  专家共识  解读

英文关键词:Late life depression  Diagnosis  Treatment  Expert consensus  Interpretation

中文摘要:

      老年期抑郁障碍（LLD）因其在病因、临床特征、评估诊断流程及治疗干预等方面的特殊性与复杂性，一直是精神科临床诊疗的难点。本文围绕《老年期抑郁障碍诊疗专家共识（2025版）》的核心内容，结合临床关注要点，系统解读该专家共识的形成背景以及LLD的风险因素、特征识别与多维整体评估、诊断及鉴别诊断、治疗策略以及康复与复发预防管理。旨在深化对该共识的理解，促进其在临床实践中的推广应用，进一步提升我国LLD的规范化诊疗水平。

英文摘要:

      Late life depression （LLD） has long been a challenge in clinical diagnosis and treatment due to its unique and complex nature in etiology， clinical features， assessment and diagnostic procedures， as well as treatment interventions. Centered on the core content of the Expert consensus on diagnosis and treatment of late life depression （2025 edition） and integrated with current clinical focuses， this article systematically interprets the consensus regarding its background， risk factors， feature identification and multidimensional assessment， diagnostic and differential principles， treatment strategies， as well as rehabilitation and recurrence prevention management of LLD. This article aims to deepen the understanding of the consensus， promote its application in clinical practice， and further elevate the level of standardized diagnosis and treatment of LLD in China. ［Funded by National Natural Science Foundation of China （number， 82171524）］